At RxClarity, we map these shifts in real time across trials, filings, and competitive pipelines so BD and Strategy teams dont miss the next inflection point
Endpoints The principal endpoint was the incidence of any malignant neoplasia during the study, reported as a serious adverse event, and the incidence of each of the tumours known as associated with obesity ( Uterine cancer, Oesophageal cancer, Thyroid cancer, Gastric cancer, Colorectal cancer, Liver cancer, Gallbladder cancer and Cholangiocarcinoma, Pancreatic cancer, Breast cancer, Ovary cancer, Kidney cancer, Meningioma, Multiple myeloma ) 6
[8] The honest framing for both is that these are surrogate endpoints body weight, HbA1c, liver fat measured over trial-length horizons
For many people, a sustainable natural alternative to GLP1 approach is judged by improved daily function, clothing fit and metabolic markers rather than only a number on the scale